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Increasing Flexibility and Automation to Maximize Efficiency || Facility Utilization & Overcoming the Gaps, Bottlenecks, and Scalability Issues to Achieve Robust and Reliable Commercial Biomanufacturing

December 11-13, 2017
  • San Diego, CA

Designed with Flexibility in Mind — Select Your Preferred Event or Attend Both for Maximum Value, Learning and Benchmarking

The adoption of innovative technologies and flexible manufacturing strategies are critical for companies to stay competitive and sustainable in a rapidly changing bioproduction landscape. These complementary, back-to-back events — Achieving Efficient Facilities and Next Frontier for Single-Use Technologies — will examine state-of-the-art facilities, technologies and processes that are being developed and implemented to handle increasingly diversified and multi-product pipelines for expanding global markets.

The first half of this uniquely crafted forum will serve as a platform to explore and determine how to achieve maximum efficiency through operational excellence, facility design, targeted process development and supply chain excellence. The second half will focus specifically on the challenges to implement single-use systems for clinical and commercial scale manufacturing. Leading experts will share case studies, practical experiences, achievements and lessons learned on the entire process, from developing and maintaining a robust supply chain, to de-bottlenecking single-use processes at full scale.

Utilizing a variety of interactive formats that encourage participation, this event will help companies determine the best strategy for building or retrofitting their existing facilities to optimize current and future production needs.

Join us at Achieving Efficient Facilities, December 11-12, to actively participate in sessions focused on approaches to:

Efficiency through Operational Excellence

  • Novel Approaches to Maximize Facility Utilization and Facility Throughput
  • Improving Efficiency for Media and Buffer Prep Support Systems
  • Lean Manufacturing and Operational Excellence
  • How to Be Multi-Product in Reality
  • Improving Turnover Time While Reducing Deviations and Down Times

Efficiency through Facility Design

  • Facility Automation —
    Impact and Cost/Labor Savings for Single-Use Facilities
  • Facility Design —
    Workflows and Logistics that Maximize the Benefits of Single-Use Technologies
  • Approaches to Minimize Upfront Investment and Maximize Flexibility
  • Lessons Learned from Commercial Single-Use Facilities
  • Hybrid Approaches
  • Closed Processing and Ballroom Classification
  • Facility in a Box —
    Lights-Out Manufacturing Facility
  • Impact of Manufacturing Platform on Facility Design

Efficiency through Innovation and Targeted Process Development

  • Innovations that Reduce the Cost of Goods — What are the risks and barriers to implementation?
  • Process Intensification to Decrease Material Use and Manufacturing Footprint
  • Scaling Down for Continuous Manufacturing
  • Emerging Innovations in Downstream Processing

Efficiency through Supply Chain Excellence

  • Managing Supply Chain —
    Strategies for High-Demand Products and Smaller Indications
    How are smaller indications addressed?
  • Supply Chain Logistics — How Much You Need and When You Need It
  • Application of Block Chain in Biopharmaceutical Industry
 

Attend Next Frontier for Single-Use Technologies, December 12-13, to explore the latest applications during sessions devoted to:

Small Scale Development and Scale Up Challenges and Success Stories

  • Standards — What are the current efforts and challenges? Why aren’t they gaining traction? What is hindering standardization efforts?
  • Component Engineering —
    Standardization and Connectivity — Improving and Modifying Connectivity to Create More Standardized Assemblies
  • Leak Testing
  • Latest Progress with BPOG/BPSA Initiatives/Working Groups
  • Ensuring Performance Reliability
  • Excipient, Extractable and Leechables Testing and Analysis
  • Developing and Maintaining a Robust Supply Chain
  • Implementing Single-Use Chromatography at Production Scale

Single-Use Facilities — Case studies

  • Incorporating Single-Use in Existing Facilities — Case Studies of Retrofitting Facilities with Single-Use Technologies
  • Integrating Automation with Single-Use Systems
  • How to De-Bottleneck Single-Use Downstream?
  • Best Practices and Achieving Regulatory Success
  • Single-Use for Vaccine Manufacturing

Single-Use of the Future

  • Single-Use Systems for Next Generation Therapies CAR-T and Other Autologous Therapies
  • What Are the Remaining Gaps for Single-Use
  • Gaps with Single-Use Sensors
  • Large Scale Bulk Freeze Solutions
  • Need for Single-Use Technologies for Continuous/Connected Processing

Small scale Development challenges

  • Challenges of Using Single-Use for a Continuous Process at Small Scale
  • Overcoming Scaling Down Challenges